| New Code(s) | Description | Explanation |
| E10.A0 | Type 1 diabetes mellitus, presymptomatic, unspecified | |
| E10.A1 | Type 1 diabetes mellitus, presymptomatic, Stage 1 | Multiple confirmed islet autoantibodies with normoglycemia |
| E10.A2 | Type 1 diabetes mellitus, presymptomatic, Stage 2 | Confirmed islet autoimmunity with dysglycemia |
| E16.A1 | Hypogylcemia level 1 | Glucose level between 54-70 mg/dL |
| E16.A2 | Hypoglycemia level 2 | Glucose level below 54 mg/dL |
| E16.A3 | Hypoglycemia level 3 | Patient experiences episode that requires assistance from another person due to confusion or unconsciousness. |
| E66.811 | Obesity, class 1 | BMI of 30.0 – 34.9 |
| E66.812 | Obesity, class 2 | BMI of 35.0 – 39.9 |
| E66.813 | Obesity, class 3 | BMI of 40.0 or greater |
| F50.01- | Various codes quantifying the severity of the patient’s restricting type anorexia nervosa | “Mild,” “Moderate”, “Severe,” and “Extreme” is defined by the patient’s BMI. “Remission” (full or partial) is determined by the clinician |
| F50.02- | Various codes quantifying the severity of the patient’s binge eating/purging type anorexia nervosa | “Mild,” “Moderate”, “Severe,” Extreme” is defined by the patient’s BMI. “Remission” (full or partial) is determined by the clinician. |
| F50.2- | Various codes quantifying the severity of the patient’s binge eating/purging type bulimia nervosa | “Mild,” “Moderate”, “Severe,” and “Extreme” is defined by the patient’s BMI. “Remission” (full or partial) is determined by the clinician. |
| F50.8- | Various codes quantifying the severity of the patient’s binge eating disorder | “Mild,” “Moderate”, “Severe,” and “Extreme” is defined by the patient’s BMI. “Remission” (full or partial) is determined by the clinician. |
| Z15.1 | Genetic susceptibility to epilepsy and neurodevelopmental disorders | |
| Z15.2 | Genetic susceptibility to obesity | |
| Z17.2- | Codes specific to progesterone receptor status | Separate codes for PR+ and PR- status |
| Z17.3- | Codes specific to human epidermal growth factor status | Separate codes for HER2+ and HER2- status |
| Z17.41 | Codes specific to hormone receptor and human epidermal growth factor receptor status | Separate codes for various combinations of positive and negative statuses. |
| Z59.71 | Insufficient health insurance coverage | Can be used to report as a contributory Social Determinant of Health (SDoH) |
| Z59.72 | Insufficient welfare support | Can be used to report as a contributory Social Determinant of Health (SDoH) |
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