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The pathogenicity of Entamoeba histolytica is discussed from an immunologic point of view. The evidence that there is some “trigger” mechanism that converts a commensal dwelling organism into a tissue invasive pathogen is rejected as inadequate.
The number of liver abscess cases in comparison with the number of intestinal amebic infections in a population is so low that this in itself suggests that a tissue invasion is a rare event in the life history of the ameba.
Pathogenicity of Entamoeba Histolytica PDF – Transmission
Entamoeba histolytica is an anaerobic parasitic amoebozoan, part of the genus Entamoeba.Predominantly infecting humans and other primates causing amoebiasis, E. histolytica is estimated to infect about 35-50 million people worldwide.
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